HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → HCID 18626199, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | 3-Chloro-4-methylaniline | HCID 7255 | — |
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 4-Methoxy-3-nitrobenzoic acid | HCID 66640 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | HCID 18626199 | HCID 18626199 | — |
Reaction Steps
Prepared according to the procedure described for Example 1 using oxalyl chloride (3.0 mL, 4.39 mmol), 4-methoxy-3-nitrobenzoic acid (5.00 g, 25.36 mmol), DMF (1.0 mL, 12.92 mmol), and 3-chloro-4-methylaniline (7.0 mL, 57.69 mmol). Chromatography on silica gel in 95:5 dichloromethane/methanol gave the product, (2.72 g), m.p. 153-157° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06268387B1 |
| Source dataset | uspto-grants-2001_07 |
| ORD ID | ord-74e3971e62774388b2475f25be98dddf |
| Source note | uspto-grants-2001_07 |