HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Amino-4-methoxybenzanilide → HCID 18626298, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Amino-4-methoxybenzanilide | HCID 8426 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 1,3-Dichloro-5-iodobenzene | HCID 76424 | — |
| Catalyst | Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI) | HCID 24350 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 18626298 | HCID 18626298 | 9.3% |
Reaction Steps
Prepared according to the procedure of Example 33 using 3-amino-4-methoxy-N-phenyl-benzamide (2.0 g, 8.3 mmol), 3,5-dichloroiodobenzene (4.5 g, 16.5 mmol), potassium carbonate (2.9 g, 21.0 mmol), and copper(I) iodide (0.5 g, 2.6 mmol) to give a gummy residue which was subjected to chromatography on a column of silica gel in dichloromethane to afford the product (0.3 g); m.p. 207-208° C. after recrystallization from ethanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06268387B1 |
| Source dataset | uspto-grants-2001_07 |
| ORD ID | ord-cbf8c73cae074bf6a2cbc256b2b2c3dc |
| Source note | uspto-grants-2001_07 |