3-Amino-4-methoxybenzanilide → HCID 17921776, compound

HRID 1387539Notes

Reaction equation

HRID 1387539 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([CH:14]=[CH:15][C:16]=1[O:17][CH3:18])[C:5]([NH:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)=[O:6].[F:19][C:20]1[C:25]([F:26])=[CH:24][C:23]([F:27])=[C:22]([F:28])[C:21]=1[N:29]=[C:30]=[S:31]>>[CH3:18][O:17][C:16]1[CH:15]=[CH:14][C:4]([C:5]([NH:7][C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[O:6])=[CH:3][C:2]=1[NH:1][C:30]([NH:29][C:21]1[C:22]([F:28])=[C:23]([F:27])[CH:24]=[C:25]([F:26])[C:20]=1[F:19])=[S:31]

Participants

3

Reactant 2

HCID 84263-Amino-4-methoxybenzanilideHCID 1407792,3,5,6-Tetrafluorophenyl isothiocyanate

Product 1

HCID 17921776HCID 17921776, compoundYield 88.6%

Procedure

Prepared according to the procedure described for Example 60 using 3-amino-4-methoxy-N-phenyl-benzamide (0.243 g, 1.0 mmol) and 2,3,5,6-tetrafluorophenyl isothiocyanate (0.224 g, 1.1 mmol) to give the product (0.398 g); m.p. 170-174° C.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-10172053efe4481c9898d77c3b6d99ee
Source dataset
uspto-grants-2001_07
Patent number
US06268387B1

Reaction notes

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