3-Amino-4-methoxybenzanilide → HCID 53917594, compound

HRID 1387544Notes

Reaction equation

HRID 1387544 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([CH:14]=[CH:15][C:16]=1[O:17][CH3:18])[C:5]([NH:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)=[O:6].[Cl:19][C:20]1[CH:25]=[CH:24][C:23]([N:26]=[C:27]=[S:28])=[CH:22][C:21]=1[N+:29]([O-:31])=[O:30]>>[Cl:19][C:20]1[CH:25]=[CH:24][C:23]([NH:26][C:27](=[S:28])[NH:1][C:2]2[CH:3]=[C:4]([CH:14]=[CH:15][C:16]=2[O:17][CH3:18])[C:5]([NH:7][C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[O:6])=[CH:22][C:21]=1[N+:29]([O-:31])=[O:30]

Participants

3

Reactant 2

HCID 84263-Amino-4-methoxybenzanilideHCID 1455814-Chloro-3-nitrophenyl isothiocyanate

Product 1

HCID 53917594HCID 53917594, compoundYield 70.9%

Procedure

Prepared according to the procedure described for Example 60 using 3-amino-4-methoxy-N-phenyl-benzamide (0.973 g, 4.00 mmol) and 4-chloro-3-nitrophenyl isothiocyanate (0.859 g, 4.00 mmol) to afford the product (1.296 g); m.p. 174-175° C.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-afa286f5653f41109fb6512b37de67fd
Source dataset
uspto-grants-2001_07
Patent number
US06268387B1

Reaction notes

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