3-Amino-4-methoxybenzanilide → HCID 18626312, compound

HRID 1387572Notes

Reaction equation

HRID 1387572 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([S:8](Cl)(=[O:10])=[O:9])[CH:5]=[CH:6][CH:7]=1.[NH2:12][C:13]1[CH:14]=[C:15]([CH:25]=[CH:26][C:27]=1[O:28][CH3:29])[C:16]([NH:18][C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1)=[O:17]>>[Cl:1][C:2]1[CH:3]=[C:4]([S:8]([NH:12][C:13]2[CH:14]=[C:15]([CH:25]=[CH:26][C:27]=2[O:28][CH3:29])[C:16]([NH:18][C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)=[O:17])(=[O:10])=[O:9])[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 84263-Amino-4-methoxybenzanilideHCID 179093-Chlorobenzenesulphonyl chloride

Product 1

HCID 18626312HCID 18626312, compoundYield 92.3%

Procedure

Prepared according to the procedure described for Example 121 using 3-chlorobenzenesulfonyl chloride (2.27 g, 10 mmol) and 3-amino-4-methoxy-N-phenyl-benzamide (2.43 g, 10.0 mmol) to afford the product (3.846 g); m.p. 197-199° C.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-d2061dd8e1a0476ca84b50b60b95a4f8
Source dataset
uspto-grants-2001_07
Patent number
US06268387B1

Reaction notes

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