3-Amino-4-methoxybenzanilide → HCID 54168795, compound

HRID 1387582Notes

Reaction equation

HRID 1387582 reaction equation
[CH2:1]([S:8](Cl)(=[O:10])=[O:9])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH2:12][C:13]1[CH:14]=[C:15]([CH:25]=[CH:26][C:27]=1[O:28][CH3:29])[C:16]([NH:18][C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1)=[O:17]>N1C=CC=CC=1>[C:2]1([CH2:1][S:8]([NH:12][C:13]2[CH:14]=[C:15]([CH:25]=[CH:26][C:27]=2[O:28][CH3:29])[C:16]([NH:18][C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)=[O:17])(=[O:10])=[O:9])[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 84263-Amino-4-methoxybenzanilideHCID 74740Phenylmethanesulfonyl chloride

Product 1

HCID 54168795HCID 54168795, compoundYield 63.1%

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

Prepared according to the procedure described for Example 121 using benzylsulfonyl chloride (1.90 g, 10 mmol), 3-amino-4-methoxy-N-phenyl-benzamide (2.43 g, 10 mmol), and pyridine (25 mL) to afford the product (2.5 g); m.p. 216-216° C. after trituration in hexanes/ethyl acetate (1:1).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-a71e42fbd9ba4e0e821d1d59e662a113
Source dataset
uspto-grants-2001_07
Patent number
US06268387B1

Reaction notes

Loading…