3-Amino-4-methoxybenzanilide → HCID 18626134, compound

HRID 1387585Notes

Reaction equation

HRID 1387585 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([S:8](Cl)(=[O:10])=[O:9])[CH:5]=[CH:6][CH:7]=1.[NH2:12][C:13]1[CH:14]=[C:15]([CH:25]=[CH:26][C:27]=1[O:28][CH3:29])[C:16]([NH:18][C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1)=[O:17]>N1C=CC=CC=1>[C:2]1([CH3:1])[CH:7]=[CH:6][CH:5]=[C:4]([S:8]([NH:12][C:13]2[CH:14]=[C:15]([CH:25]=[CH:26][C:27]=2[O:28][CH3:29])[C:16]([NH:18][C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)=[O:17])(=[O:10])=[O:9])[CH:3]=1

Participants

4

Reactant 2

HCID 84263-Amino-4-methoxybenzanilideHCID 27345953-Methylbenzenesulphonyl chloride

Product 1

HCID 18626134HCID 18626134, compoundYield 90.5%

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

Prepared according to the procedure described for Example 121 using 3-methylbenzenesulfonyl chloride (1.91 g, 10 mmol), 3-amino-4-methoxy-N-phenyl-benzamide (2.43 g, 10 mmol), and pyridine (25 mL) to afford the product (3.587 g); m.p. 195-197° C. after trituration in hexanes/ethyl acetate (1:1).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-6320d108e86b4f03b66e002a03b5cafb
Source dataset
uspto-grants-2001_07
Patent number
US06268387B1

Reaction notes

Loading…