Methyl 3-hydroxy-4-methoxybenzoate → 1,1-Dimethylethyl 7-({2-(methyloxy)-5-[(methyloxy)carbonyl]phenyl}oxy)-1,2,4,5-tetrahydro-3H-3-benzazepine-3-carboxylate

HRID 138762Notes

Reaction equation

HRID 138762 reaction equation
[CH3:1][C:2]([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][c:11]2[c:12]([cH:15][cH:16][c:17]([B:19]([OH:20])[OH:21])[cH:18]2)[CH2:13][CH2:14]1.[CH3:22][O:23][C:24]([c:25]1[cH:26][c:27]([OH:33])[c:28]([O:31][CH3:32])[cH:29][cH:30]1)=[O:34]>>[CH3:1][C:2]([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][c:11]2[c:12]([cH:15][cH:16][c:17]([O:33][c:27]3[cH:26][c:25]([C:24]([O:23][CH3:22])=[O:34])[cH:30][cH:29][c:28]3[O:31][CH3:32])[cH:18]2)[CH2:13][CH2:14]1

Participants

3

Reactant 2

HCID 4056967Methyl 3-hydroxy-4-methoxybenzoateHCID 57440296(3-(tert-Butoxycarbonyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)boronic acid

Product 1

HCID 574403011,1-Dimethylethyl 7-({2-(methyloxy)-5-[(methyloxy)carbonyl]phenyl}oxy)-1,2,4,5-tetrahydro-3H-3-benzazepine-3-carboxylate

Sources & evidence

ORD record
ord-ff828224762d450dbe96f5f244b0ae17
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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