Aniline → N-(2-Nitrophenyl)-N'-phenyl-urea

HRID 1387667Notes

Reaction equation

HRID 1387667 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[N:10]=[C:11]=[O:12])([O-:3])=[O:2].[NH2:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1.CCCCCC>C1(C)C=CC=CC=1>[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[NH:10][C:11]([NH:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)=[O:12])([O-:3])=[O:2]

Participants

5

Reactant 3

HCID 6115AnilineHCID 8058HexaneHCID 768342-Nitrophenyl isocyanate

Product 1

HCID 4109613N-(2-Nitrophenyl)-N'-phenyl-urea

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Conditions

Temperature
20 °C

Procedure

To a solution of 2-Nitrophenyl isocyanate (3.34 g) in 100 mL of toluene was added aniline (2 g). The mixture was stirred at 20° C. for 30 min. Hexane (300 mL) was added and the resulting solid was filtered and dried to yield N-(2-Nitrophenyl)-N′-phenyl-urea as a light yellow solid.

Workup

  1. filtrationthe resulting solid was filtered
  2. customdried

Sources & evidence

ORD record
ord-72ccf82ff4394f408398ad97a5f16eff
Source dataset
uspto-grants-2001_07
Patent number
US06268496B1

Reaction notes

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