Toluene → 4-(6-(Bromomethyl)-2-chlorothieno[3,2-d]pyrimidin-4-yl)morpholine

HRID 138788Notes

Reaction equation

HRID 138788 reaction equation
[CH3:23][c:24]1[cH:25][cH:26][cH:27][cH:28][cH:29]1.[CH:30]([Cl:31])([Cl:32])[Cl:33].[Cl:1][c:2]1[n:3][c:4]([N:13]2[CH2:14][CH2:15][O:16][CH2:17][CH2:18]2)[c:5]2[c:6]([n:7]1)[cH:8][c:9]([CH2:11][OH:12])[s:10]2.[P:19]([Br:20])([Br:21])[Br:22]>>[Cl:1][c:2]1[n:3][c:4]([N:13]2[CH2:14][CH2:15][O:16][CH2:17][CH2:18]2)[c:5]2[c:6]([n:7]1)[cH:8][c:9]([CH2:11][Br:20])[s:10]2

Participants

5

Reactant 4

HCID 1140TolueneHCID 6212ChloroformHCID 24614Phosphorus tribromideHCID 46180605(2-Chloro-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methanol

Product 1

HCID 461807264-(6-(Bromomethyl)-2-chlorothieno[3,2-d]pyrimidin-4-yl)morpholine

Sources & evidence

ORD record
ord-3e9b6626e5c648d2a9c700fd7d9ee10b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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