HCID 18472377, compound → HCID 18472500, compound

Participants

Reaction Steps

A mixture of 4-nitrobenzyldipropylphosphine oxide (3.0 g) and 5% Pd—C (0.3 g) in ethanol (50 ml) was vigorously stirred under hydrogen atmosphere for 16 hours, and the Pd—C was filtered off. The filtrate was concentrated under reduced pressure. The residue was separated and purified with column chromatography (ethanol/ethyl acetate=1:5→1:4) and recrystallized from ethanol-ethyl acetate to give 4-aminobenzyldipropylphosphine oxide (1.78 g) as colorless crystals.

Provenance & Evidence