HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formaldehyde → 8-Cyclopentyl-2-methyleneoctanoic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formaldehyde | HCID 712 | — |
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | (6-Cyclopentylhexyl)-malonic acid ethyl ester | HCID 53998515 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | 8-Cyclopentyl-2-methyleneoctanoic acid ethyl ester | HCID 54242028 | — |
Reaction Steps
11.5 g of 8-cyclopentyl-2-methyleneoctanoic acid ethyl ester, in the form of a nearly colourless oil, which is purified by chromatography on silica gel (migrating agent: 95:5 petroleum ether/ethyl acetate), are obtained by the procedure described in Example (1b) from 22.1 g of (6-cyclopentylhexyl)-malonic acid ethyl ester, 2.8 g of paraformaldehyde, 22 ml of pyridine and 1 ml of piperidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04430339 |
| Source dataset | uspto-grants-1984_02 |
| ORD ID | ord-e457a980f0764d14a271e7f072abb0c6 |
| Source note | uspto-grants-1984_02 |