1-Hexanol → HCID 20040568, compound

Participants

Reaction Steps

5 Parts of methyl 5-(4-t-butyl-2,5-dihydroxyphenyl)-5-methylhexanoate is converted to the corresponding n-hexyl ester after reaction with 20 parts n-hexanol and 0.25 part of sodium methoxide in a sealed glass tube for 7 days. The reaction mixture is diluted with ether, washed with dilute hydrochloric acid, then water, and stripped of ether and excess hexanol under reduced pressure to give a residue. Short-path distillation of the residue at 0.4 mb yields n-hexyl 5-(4-t-butyl-2,5-dihydroxyphenyl)-5-methyl-hexanoate [formula (125)] as an amber oil with the following percentage composition by weight:

Provenance & Evidence