tert-Butanol → HCID 86739228, compound

HRID 1388260Notes

Reaction equation

HRID 1388260 reaction equation
[CH3:1][C:2]1([CH3:13])[C@H:4](/[CH:5]=[CH:6]/[C:7](=[O:9])[CH3:8])[C@H:3]1[C:10](Cl)=[O:11].[C:14]([OH:18])([CH3:17])([CH3:16])[CH3:15]>C1C=CC=CC=1>[CH3:1][C:2]1([CH3:13])[C@H:4](/[CH:5]=[CH:6]/[C:7](=[O:9])[CH3:8])[C@H:3]1[C:10]([O:18][C:14]([CH3:17])([CH3:16])[CH3:15])=[O:11]

Participants

4

Reactant 2

HCID 6386tert-ButanolHCID 131713381HCID 131713381, compound

Product 1

HCID 86739228HCID 86739228, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

Using the procedure of Example 3, 2.9 g of (1R,trans) 2,2-dimethyl-3-[(E)-3-oxo-1-butenyl]-cyclopropane-1-carboxylic acid chloride and 1.4 ml of tert.-butanol were reacted to obtain 1.43 g of tert.-butyl (1R,trans) 2,2-dimethyl-3-[(E)-3-oxo-1-butenyl]-cyclopropane-1-carboxylate with a specific rotation of [α]D20 =+67°±4° (c=0.25% in benzene).

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-ca838601dc36472da5561d9db596d255
Source dataset
uspto-grants-1984_02
Patent number
US04431576

Reaction notes

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