tert-Butanol → HCID 86739235, compound

HRID 1388264Notes

Reaction equation

HRID 1388264 reaction equation
[CH3:1][C:2]1([CH3:14])[C@H:4](/[CH:5]=[CH:6]/[C:7]([O:9][CH3:10])=[O:8])[C@H:3]1[C:11](Cl)=[O:12].[C:15]([OH:19])([CH3:18])([CH3:17])[CH3:16]>C1C=CC=CC=1.C(Cl)(Cl)Cl>[CH3:1][C:2]1([CH3:14])[C@H:4](/[CH:5]=[CH:6]/[C:7]([O:9][CH3:10])=[O:8])[C@H:3]1[C:11]([O:19][C:15]([CH3:18])([CH3:17])[CH3:16])=[O:12]

Participants

5

Reactant 2

HCID 6386tert-ButanolHCID 131713383HCID 131713383, compound

Product 1

HCID 86739235HCID 86739235, compound

Reagents, catalysts & solvents 2

HCID 241BenzeneSolventHCID 6212ChloroformSolvent

Procedure

Using the procedure of Example 3, 2.7 g of (1R,trans) 2,2-dimethyl-3-[(E)-3-methoxy-3-oxo-1-propenyl]-cyclopropane-1-carboxylic acid chloride in 12.5 ml of benzene and 1.23 ml of tert.-butanol were reacted to obtain 1.05 g of tert.-butyl (1R,trans) 2,2-dimethyl-3-[(E)-3-methoxy-3-oxo-1-propenyl]-cyclopropane-1-carboxylate melting at 67° C. with a specific rotation of [α]D20 =+75.5°±2° (c=0.5% in chloroform).

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-7d0e80e3620e4ca0b2bbf5e0ecf90927
Source dataset
uspto-grants-1984_02
Patent number
US04431576

Reaction notes

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