HRID1388274

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID11332901

Carbamimidic acid, N,N'-bis(1-methylethyl)-, 1-methylethyl ester

C10H22N2O

$结构：CC1(C)[C@H](C(=O)O)[C@@H]1/C=C1\CCOC1=O$

HCID70503105

未命名化合物

PRODUCTS

生成物

$结构：CC(C)OC(=O)[C@@H]1[C@H](/C=C2\CCOC2=O)C1(C)C$

HCID86739246

未命名化合物

收率 49.2%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID241

Benzene

C6H6

PROCEDURE

实验过程

Using the procedure of Example 17, 8.4 g of (1R,cis) 2,2-dimethyl-3-[(E) (dihydro-2-oxo-3-(2H)-furanylidene)-methyl]-cyclopropane-1-carboxylic acid and 7.45 g of isopropyl N,N'-diisopropylcarbamimidate were reacted to obtain 4.96 g of isopropyl (1R,cis) 2,2-dimethyl-3-[(E) (dihydro-2-oxo-3-(2H)-furanylidene)-methyl]-cyclopropane-1-carboxylate with a specific rotation of [α]D20 =+41°±2.5° (c=0.5% in benzene).

WORKUP

后处理

customwere reacted