Dimethyl Sulfate → HCID 53983477, compound

HRID 1388472Notes

Reaction equation

HRID 1388472 reaction equation
[OH:1][N:2]=[C:3]([C:9]1[N:10]=[C:11]([CH3:14])[S:12][CH:13]=1)[C:4]([O:6][CH2:7][CH3:8])=[O:5].S(OC)(O[CH3:19])(=O)=O>>[CH3:19][O:1][N:2]=[C:3]([C:9]1[N:10]=[C:11]([CH3:14])[S:12][CH:13]=1)[C:4]([O:6][CH2:7][CH3:8])=[O:5]

Participants

3

Reactant 2

HCID 6497Dimethyl SulfateHCID 73178131Ethyl 2-hydroxyimino-2-(2-methyl-1,3-thiazol-4-yl)acetate

Product 1

HCID 53983477HCID 53983477, compoundYield 84.5%

Procedure

Ethyl 2-hydroxyimino-2-(2-methyl-1,3-thiazol-4-yl)acetate (anti isomer) (0.3 g.) and dimethyl sulfate (0.18 g.) were reacted according to a similar manner to that of Preparation 8-5) to give pale yellow oil of ethyl 2-methoxyimino-2-(2-methyl-1,3-thiazol-4-yl)acetate (anti isomer) (0.27 g.).

Workup

  1. customof Preparation 8-5)

Sources & evidence

ORD record
ord-ff7018ad7eaf464582efec1ab7d9c514
Source dataset
uspto-grants-1984_02
Patent number
US04431643

Reaction notes

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