Fumaric Acid → HCID 20471295, compound

HRID 1388508Notes

Reaction equation

HRID 1388508 reaction equation
[C:1]([OH:8])(=[O:7])/[CH:2]=[CH:3]/[C:4]([OH:6])=[O:5].[CH3:9][C:10]1[CH:11]=[C:12]([CH:19]=[CH:20][C:21]=1[CH3:22])[CH2:13][N:14]1[CH:18]=[CH:17][N:16]=[CH:15]1>C(O)C>[C:1]([OH:8])(=[O:7])/[CH:2]=[CH:3]/[C:4]([OH:6])=[O:5].[CH3:9][C:10]1[CH:11]=[C:12]([CH:19]=[CH:20][C:21]=1[CH3:22])[CH2:13][N:14]1[CH:18]=[CH:17][N:16]=[CH:15]1

Participants

4

Reactant 2

HCID 444972Fumaric AcidHCID 130453671-[(3,4-Dimethylphenyl)methyl]-1H-imidazole

Product 1

HCID 20471295HCID 20471295, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

A solution of fumaric acid (0.29 g, 0.0025 mol) in hot ethanol (10 ml) was added to a stirred solution of 1-(3,4-dimethylbenzyl)imidazole (0.46 g, 0.0025 mol) in hot ethanol (10 ml). After boiling for 0.25 h, the solution was evaporated to afford a white solid. Recrystallisation of the solid from ethyl acetate afforded 1-(3,4-dimethylbenzyl)imidazole hydrogen fumarate 1/6 hydrate as a white solid m.p. 138°-140°.

Workup

  1. customthe solution was evaporated
  2. customto afford a white solid
  3. customRecrystallisation of the solid from ethyl acetate

Sources & evidence

ORD record
ord-ed9b92d4b7a3405c888685f8862e4b86
Source dataset
uspto-grants-1984_02
Patent number
US04431815

Reaction notes

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