Fumaric Acid → HCID 20471299, compound

HRID 1388514Notes

Reaction equation

HRID 1388514 reaction equation
[C:1]([OH:8])(=[O:7])/[CH:2]=[CH:3]/[C:4]([OH:6])=[O:5].[Br:9][C:10]1[CH:21]=[CH:20][CH:19]=[CH:18][C:11]=1[CH2:12][N:13]1[CH:17]=[CH:16][N:15]=[CH:14]1>C(O)C>[C:1]([OH:8])(=[O:7])/[CH:2]=[CH:3]/[C:4]([OH:6])=[O:5].[Br:9][C:10]1[CH:21]=[CH:20][CH:19]=[CH:18][C:11]=1[CH2:12][N:13]1[CH:17]=[CH:16][N:15]=[CH:14]1

Participants

4

Reactant 2

HCID 444972Fumaric AcidHCID 132693191-[(2-Bromophenyl)methyl]-1H-imidazole

Product 1

HCID 20471299HCID 20471299, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

A solution of fumaric acid (0.18 g) in hot ethanol (10 ml) was added to a solution of 1-(2-bromobenzyl)imidazole (0.4 g) in hot ethanol (5 ml). After boiling for 10 minutes, the solution was evaporated under reduced pressure to afford a white solid. Recrystallisation of the solid from propan-2-ol gave 1-(2-bromobenzyl)imidazole hydrogen fumarate, m.p. 158°-159°.

Workup

  1. customthe solution was evaporated under reduced pressure
  2. customto afford a white solid
  3. customRecrystallisation of the solid from propan-2-ol

Sources & evidence

ORD record
ord-34fd0bd9e56a4dff8b25abd9f5ac1ad3
Source dataset
uspto-grants-1984_02
Patent number
US04431815

Reaction notes

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