Ethanol, 2-(1,4-benzodioxan-2-yl)- → 2-(2-Tosyloxyethyl)-1,4-benzodioxan

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Reaction Steps

74 g of 2-(2-hydroxyethyl) (2,3-dihydro [4H] 1,4-benzodioxin) are dissolved in 150 ml pyridine and to this solution 76 g p toluene sulfochloride are added while maintaining the inner temperature beneath 25°. The whole mixture is kept under stirring at room temperature for 24 hours then poured in water and extracted with chloroform. The chloroformic solutions are united, washed with water, dried and evaporated off. The dry residue is further purified by recrystallizing it from a mixture isopropyl ether--petrol (50:50)

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