HRID1388686

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(C)C[C@H](NC(=O)[C@@H](N)Cc1ccccc1)C(=O)OCc1ccccc1.Cl

HCID70633701

未命名化合物

HCID178527035

未命名化合物

PRODUCTS

生成物

结构：CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NP(=O)(CCCCc1ccccc1)OCc1ccccc1)C(=O)OCc1ccccc1

HCID131713391

未命名化合物

PROCEDURE

实验过程

(4-Phenylbutyl)phosphinic acid, phenylmethyl ester is reacted with L-phenylalanyl-L-leucine, phenylmethyl ester, hydrochloride according to the procedure of Example 1(c) to yield N-[N-[phenyl-methoxy(4-phenylbutyl)phosphinyl]-L-phenylalanyl]-L-leucine, phenylmethyl ester.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-e7c7440cc9834b2383410e9de36da726
来源数据集: uspto-grants-1984_02
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04432972
来源说明: uspto-grants-1984_02

反应 SMILES

[C:1]1([CH2:7][CH2:8][CH2:9][CH2:10][PH:11](=[O:20])[O:12][CH2:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Cl.[NH2:22][C@H:23]([C:31]([NH:33][C@H:34]([C:39]([O:41][CH2:42][C:43]1[CH:48]=[CH:47][CH:46]=[CH:45][CH:44]=1)=[O:40])[CH2:35][CH:36]([CH3:38])[CH3:37])=[O:32])[CH2:24][C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1>>[C:14]1([CH2:13][O:12][P:11]([CH2:10][CH2:9][CH2:8][CH2:7][C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)([NH:22][C@H:23]([C:31]([NH:33][C@H:34]([C:39]([O:41][CH2:42][C:43]2[CH:44]=[CH:45][CH:46]=[CH:47][CH:48]=2)=[O:40])[CH2:35][CH:36]([CH3:38])[CH3:37])=[O:32])[CH2:24][C:25]2[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=2)=[O:20])[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1