HRID1388689

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(C)C[C@H](NC(=O)[C@@H](N)Cc1ccccc1)C(=O)OCc1ccccc1.Cl

HCID70633701

未命名化合物

HCID178527034

未命名化合物

PRODUCTS

生成物

结构：CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NP(=O)(CCc1ccccc1)OCc1ccccc1)C(=O)OCc1ccccc1

HCID131713393

未命名化合物

PROCEDURE

实验过程

(2-Phenylethyl)phosphinic acid, phenylmethyl ester is reacted with L-phenylalanyl-L-leucine, phenylmethyl ester, hydrochloride salt according to the procedure of Example 1(c) to yield N-[N-[(2-phenylethyl)(phenylmethoxy)phosphinyl]-L-phenylalanyl]-L-leucine, phenylmethyl ester.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-31aba4bc965a44538c2fbac30a587d9a
来源数据集: uspto-grants-1984_02
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04432972
来源说明: uspto-grants-1984_02

反应 SMILES

[C:1]1([CH2:7][CH2:8][PH:9](=[O:18])[O:10][CH2:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Cl.[NH2:20][C@H:21]([C:29]([NH:31][C@H:32]([C:37]([O:39][CH2:40][C:41]1[CH:46]=[CH:45][CH:44]=[CH:43][CH:42]=1)=[O:38])[CH2:33][CH:34]([CH3:36])[CH3:35])=[O:30])[CH2:22][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1>>[C:1]1([CH2:7][CH2:8][P:9]([O:10][CH2:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)([NH:20][C@H:21]([C:29]([NH:31][C@H:32]([C:37]([O:39][CH2:40][C:41]2[CH:42]=[CH:43][CH:44]=[CH:45][CH:46]=2)=[O:38])[CH2:33][CH:34]([CH3:36])[CH3:35])=[O:30])[CH2:22][C:23]2[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=2)=[O:18])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1