HRID1388690

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(C)C[C@H](NC(=O)[C@@H](N)Cc1ccccc1)C(=O)OCc1ccccc1.Cl

HCID70633701

未命名化合物

HCID178445555

未命名化合物

PRODUCTS

生成物

结构：CCCCCCP(=O)(N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)OCc1ccccc1)OCc1ccccc1

HCID131713394

未命名化合物

PROCEDURE

实验过程

Hexylphosphinic acid, phenylmethyl ester is reacted with L-phenylalanyl-L-leucine, phenylmethyl ester, hydrochloride salt according to the procedure of Example 1(c) to yield N-[N-[hexyl(phenylmethoxy)phosphinyl]-L-phenylalanyl]-L-leucine, phenylmethyl ester.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-4eb7d16c0d67427088d8adebb65ee89e
来源数据集: uspto-grants-1984_02
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04432972
来源说明: uspto-grants-1984_02

反应 SMILES

[CH2:1]([PH:7](=[O:16])[O:8][CH2:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6].Cl.[NH2:18][C@H:19]([C:27]([NH:29][C@H:30]([C:35]([O:37][CH2:38][C:39]1[CH:44]=[CH:43][CH:42]=[CH:41][CH:40]=1)=[O:36])[CH2:31][CH:32]([CH3:34])[CH3:33])=[O:28])[CH2:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>>[CH2:1]([P:7]([O:8][CH2:9][C:10]1[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=1)([NH:18][C@H:19]([C:27]([NH:29][C@H:30]([C:35]([O:37][CH2:38][C:39]1[CH:40]=[CH:41][CH:42]=[CH:43][CH:44]=1)=[O:36])[CH2:31][CH:32]([CH3:34])[CH3:33])=[O:28])[CH2:20][C:21]1[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=1)=[O:16])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6]