Sulfuric Acid → HCID 20470040, compound

HRID 1388728Notes

Reaction equation

HRID 1388728 reaction equation
[NH2:1][C:2]1[CH2:6][CH2:5][N:4]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[N:3]=1.[S:13](=[O:17])(=[O:16])([OH:15])[OH:14]>C(O)C>[S:13]([OH:17])([OH:16])(=[O:15])=[O:14].[NH2:1][C:2]1[CH2:6][CH2:5][N:4]([C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=2)[N:3]=1

Participants

4

Reactant 2

HCID 1118Sulfuric AcidHCID 987363-Amino-1-phenylpyrazole

Product 1

HCID 20470040HCID 20470040, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A 2.0 g. amount of 3-amino-1-phenyl-2-pyrazoline (Example 1) is dissolved in 200 ml. of absolute ethanol, then 4.0 ml. of 10% w/w sulfuric acid solution is added with stirring. The reaction mixture is allowed to stand for 2 hours at room temperature then is filtered. The precipitate is refluxed with 100 ml. of acetone, cooled and filtered to give 1.40 g. of the desired product, m.p. 181°-183° C.

Workup

  1. filtrationthen is filtered
  2. temperatureThe precipitate is refluxed with 100 ml
  3. temperatureof acetone, cooled
  4. filtrationfiltered
  5. customto give 1.40 g

Sources & evidence

ORD record
ord-a3993fa730104092834c12108b2a5064
Source dataset
uspto-grants-1984_02
Patent number
US04432991

Reaction notes

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