Ethyl 2-bromopropionate → Ethyl alpha-[p-(3-methyl-2-butenyl)phenyl]propionate

HRID 1388809Notes

Reaction equation

HRID 1388809 reaction equation
[CH3:1][C:2]([CH3:12])=[CH:3][CH2:4][C:5]1[CH:10]=[CH:9][C:8]([Cu])=[CH:7][CH:6]=1.Br[CH:14]([CH3:20])[C:15]([O:17][CH2:18][CH3:19])=[O:16]>>[CH3:1][C:2]([CH3:12])=[CH:3][CH2:4][C:5]1[CH:10]=[CH:9][C:8]([CH:14]([CH3:20])[C:15]([O:17][CH2:18][CH3:19])=[O:16])=[CH:7][CH:6]=1

Participants

3

Reactant 2

HCID 79040Ethyl 2-bromopropionateHCID 178442162HCID 178442162, compound

Product 1

HCID 13118083Ethyl alpha-[p-(3-methyl-2-butenyl)phenyl]propionateYield 6.7%

Procedure

In the same way as in Comparative Example 7, p-(3-methyl-2-butenyl)phenyl copper (I) was reacted with ethyl α-bromopropionate. Ethyl α-[p-(3-methyl-2-butenyl)phenyl]propionate was obtained in an amount of 1.64 g (yield 6.7%).

Sources & evidence

ORD record
ord-788a510f1135411b89449aeb769f635d
Source dataset
uspto-grants-1984_02
Patent number
US04433160

Reaction notes

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