HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium ethoxide → HCID 13277458, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium ethoxide | HCID 2723922 | — |
| Reactant | HCID 13277456 | HCID 13277456 | — |
| Product | HCID 13277458 | HCID 13277458 | 56.4% |
Reaction Steps
3.0 g N-(4,6-dimethoxy-5-pyrimidyl)-thiourea are mixed with a sodium-ethylate solution (0.317 g sodium in 30 ml absolute ethanol) and heated for 3 hours under reflux. After cooling the mixture is neutralized. The reaction product is vacuum treated and purified chromatographically on silica gel (developer; chloroform/methanol 95:5). 0.6 g N-(4-ethoxy-6-methoxy-5-pyrimidyl)-thiourea having a melting point of 186° to 187° C. are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04434167 |
| Source dataset | uspto-grants-1984_02 |
| ORD ID | ord-5f9080d880d346a98b85bc67ec77dbe7 |
| Source note | uspto-grants-1984_02 |