HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,3-Dimethoxybenzoic acid → 5-(Chlorosulfonyl)-2,3-dimethoxybenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,3-Dimethoxybenzoic acid | HCID 15204 | — |
| Reactant | Chlorosulfonic acid | HCID 24638 | — |
| Solvent | Water | HCID 962 | — |
| Product | 5-(Chlorosulfonyl)-2,3-dimethoxybenzoic acid | HCID 3018528 | 81.1% |
Reaction Steps
To a solution, cooled to -5° C., of 511.7 g (200 ml) of chlorosulfonic acid (ClSO3H) are slowly added 80 g of 2,3-dimethoxy benzoic acid. Then the temperature is allowed to rise to 15° C., the mixture is poured into a solution of water and ice, and the precipitate formed is filtered. Thus, 100 g (yield: 80%) of 5-chlorosulfonyl 2,3-dimethoxy benzoic acid are obtained [(IIb), Melting point: 157° C⟧
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04434170 |
| Source dataset | uspto-grants-1984_02 |
| ORD ID | ord-63604e198f3344e5be8bbd4700af8d39 |
| Source note | uspto-grants-1984_02 |