Benzimidazole → HCID 20469032, compound

HRID 1388912Notes

Reaction equation

HRID 1388912 reaction equation
[N:1]1([CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][NH2:15])[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[CH:2]1.BrCCCCCN1[C:26](=[O:27])[C:25]2=[CH:28][CH:29]=[CH:30][CH:31]=[C:24]2[C:23]1=[O:32].N1C2C=CC=CC=2N=C1>>[C:23]1(=[O:32])[N:15]([CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][N:1]2[C:5]3[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=3[N:3]=[CH:2]2)[C:26](=[O:27])[C:25]2=[CH:28][CH:29]=[CH:30][CH:31]=[C:24]12

Participants

4

Reactant 3

HCID 5798BenzimidazoleHCID 136770N-(5-Bromopentyl)phthalimideHCID 20469057HCID 20469057, compound

Product 1

HCID 20469032HCID 20469032, compound

Procedure

In this case, the 1H-benzimidazole-1-pentanamine used as the starting material was obtained by first reacting N-(5-bromopentyl)phthalimide with 1H-benzimidazole to give 1-(5-phthalimidopentyl)-1H-benzimidazole which was then treated with hydrazine to give the amine, all according to general procedures known in the art (Houben-Weyl, Vol. XI/1, page 82, George Thieme Verlag, Stuttgart, 1957).

Workup

  1. customwas obtained

Sources & evidence

ORD record
ord-5289de48fd2e4fd1b149bafde2fd4fba
Source dataset
uspto-grants-1984_02
Patent number
US04434174

Reaction notes

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