反应详情

The procedure of Example 15 was employed utilizing ethyl-2-(4'-chlorobenzoyl)-3-dimethylaminopropenoate in lieu of ethyl-2-benzoyl-3-dimethylaminopropenoate to yield ethyl-5-(4'-chlorophenyl)-4-isoxazolecarboxylate (3.7 g.; 49% yield) having a melting point of 58°-60° C. and the following analysis: