HCID 53986482, compound → HCID 22221361, compound

HRID 1389010Notes

Reaction equation

HRID 1389010 reaction equation
[CH2:1]([O:3][C:4](=[O:20])[C:5]([C:10](=[O:19])[C:11]1[CH:16]=[CH:15][C:14]([O:17][CH3:18])=[CH:13][CH:12]=1)=[CH:6][N:7](C)C)[CH3:2].C(OC(=O)C(C(=O)C1C=CC=CC=1)=CN(C)C)C>>[CH2:1]([O:3][C:4]([C:5]1[CH:6]=[N:7][O:19][C:10]=1[C:11]1[CH:16]=[CH:15][C:14]([O:17][CH3:18])=[CH:13][CH:12]=1)=[O:20])[CH3:2]

Participants

3

Reactant 2

HCID 53986482HCID 53986482, compoundHCID 54499154Ethyl-2-benzoyl-3-dimethylaminopropenoate

Product 1

HCID 22221361HCID 22221361, compoundYield 61%

Procedure

The procedure of Example 15 was employed utilizing ethyl-2-(4'-methoxybenzoyl)-3-dimethylaminopropenoate in lieu of ethyl-2-benzoyl-3-dimethylaminopropenoate to yield ethyl-5-(4'-methoxyphenyl)-4-isoxazolecarboxylate (1.5 g.; 61% yield) having a melting point of 57°-59° C. and the following analysis:

Sources & evidence

ORD record
ord-f9d0fc4ade9349cca70cbf14e6b0aae3
Source dataset
uspto-grants-1981_01
Patent number
US04243406

Reaction notes

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