Ethanolamine → 2-[(1,1-Dioxidotetrahydro-3-thienyl)amino]ethanol hydrochloride

HRID 1389025Notes

Reaction equation

HRID 1389025 reaction equation
[CH2:1]([CH2:3][NH2:4])[OH:2].[ClH:5].[S:6]1(=[O:13])(=[O:12])[CH2:10][CH2:9][CH:8](N)[CH2:7]1>>[ClH:5].[OH:2][CH2:1][CH2:3][NH:4][CH:8]1[CH2:9][CH2:10][S:6](=[O:13])(=[O:12])[CH2:7]1

Participants

3

Reactant 2

HCID 700EthanolamineHCID 27952013-Aminotetrahydrothiopene 1,1-dioxide hydrochloride

Product 1

HCID 168963702-[(1,1-Dioxidotetrahydro-3-thienyl)amino]ethanol hydrochloride

Procedure

The procedure of Example 1 was repeated substituting 95 percent monoethanolamine (28.6 parts) for the ammonium hydroxide of Example 1. A sticky solid was filtered after treatment with hydrochloric acid, and upon drying in vacuo over P2O5 weighed 59.6 g. (78.5 percent of theory) m.p. 122°-124° C.

Workup

  1. filtrationA sticky solid was filtered after treatment with hydrochloric acid
  2. dry with materialupon drying in vacuo over P2O5

Sources & evidence

ORD record
ord-38af3356ef5e4de0be77b386ac5839e0
Source dataset
uspto-grants-1981_01
Patent number
US04243524

Reaction notes

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