HCID 20298259, compound → HCID 20298257, compound

HRID 1389132Notes

Reaction equation

HRID 1389132 reaction equation
[CH:1]1(/[CH:4]=[CH:5]/[C:6]2[NH:7][CH:8]=[CH:9][CH:10]=2)[CH2:3][CH2:2]1>C(O)C.[Pd]>[CH:1]1([CH2:4][CH2:5][C:6]2[NH:7][CH:8]=[CH:9][CH:10]=2)[CH2:3][CH2:2]1

Participants

4

Reactant 1

HCID 20298259HCID 20298259, compound

Product 1

HCID 20298257HCID 20298257, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

A solution of cis-/trans-2-(2-cyclopropylvinyl)-pyrrole (1.7 g., 0.073 mole) in ethanol (100 ml.) was hydrogenated over 10% palladium on charcoal at room temperature and 3.5 kg./cm2 (50 p.s.i.). The solution was filtered, the solvent evaporated and the residue distilled to give the required 2-(2-cyclopropylethyl)pyrrole as an oil (4.93 g.), B.P. 100°-103°./13 mm.

Workup

  1. filtrationThe solution was filtered
  2. customthe solvent evaporated
  3. distillationthe residue distilled

Sources & evidence

ORD record
ord-51658f600e024ed788edcfca8cc8c298
Source dataset
uspto-grants-1981_01
Patent number
US04243672

Reaction notes

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