HCID 54192454, compound → HCID 20298527, compound

Participants

Reaction Steps

Ethyl 3-(4-fluoro-6-methoxy-2-naphthyl)-but-2-enoate (12 g) was dissolved in ethyl acetate (100 ml) and 5% palladium on charcoal (1.5 g) was added. The mixture was shaken under a hydrogen atmosphere until uptake of hydrogen ceased (ca. 1 hour). The catalyst was removed by filtration through a celite bed and the solvent was removed under reduced pressure to give ethyl 3-(4-fluoro-6-methoxy-2-naphthyl)-butanoate as an oil (11.9 g., 98%).

Provenance & Evidence