HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzylamine → 4-(Benzylamino)butanenitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzylamine | HCID 7504 | — |
| Reactant | Cyclohexane | HCID 8078 | — |
| Reactant | 4-Bromobutyronitrile | HCID 21412 | — |
| Reactant | 1-Phenylmethanamine--hydrogen bromide (1/1) | HCID 12998568 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 4-(Benzylamino)butanenitrile | HCID 3014570 | 66% |
Reaction Steps
32.2 g of benzylamine, 14.8 g of 4-bromobutyronitrile and 30 ml of cyclohexane are stirred at room temperature for 12 hours. After the addition of diethyl ether the separated benzylamine hydrobromide is filtered off; the ether phase is washed with water, dried and concentrated by evaporation. The residue is distilled in vacuo to yield 11.5 g (66% of theory) of 4-benzylaminobutyronitrile (B.P. 114° to 120°/0.05 mm Hg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04243678 |
| Source dataset | uspto-grants-1981_01 |
| ORD ID | ord-3d7c63796250464c962ef37264c77f02 |
| Source note | uspto-grants-1981_01 |