tert-Octylamine → HCID 20292065, compound

HRID 1389204Notes

Reaction equation

Br[CH2:2][CH2:3][CH2:4][C:5]([O:7]CC)=[O:6].[CH3:10][C:11]([NH2:18])([CH3:17])[CH2:12][C:13]([CH3:16])([CH3:15])[CH3:14].[C:19](Cl)(=[O:23])/[CH:20]=[CH:21]/[CH3:22]>>[C:19]([N:18]([C:11]([CH3:17])([CH3:10])[CH2:12][C:13]([CH3:16])([CH3:15])[CH3:14])[CH2:2][CH2:3][CH2:4][C:5]([OH:7])=[O:6])(=[O:23])/[CH:20]=[CH:21]/[CH3:22]

Participants

Reactant 3

HCID 61017tert-Octylamine

HCID 76300Ethyl 4-bromobutyrate

HCID 643131trans-Crotonyl chloride

Product 1

HCID 20292065HCID 20292065, compound

Procedure

Analogously to Example 1, ethyl N-crotonoyl-4-[(1,1,3,3-tetramethylbutyl)amino]butyrate is obtained as a viscous oil by reacting the reaction product of ethyl 4-bromobutyrate and 1,1,3,3-tetramethylbutylamine with crotonic acid chloride, the saponification of which yields N-crotonoyl-4-[(1,1,3,3-tetramethylbutyl)amino]butyric acid (M.P. 92° to 93°).

Sources & evidence

ORD record: ord-a884bc4b71604dbd8e780956c31f12ff
Source dataset: uspto-grants-1981_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04243678

Reaction notes

Loading…