Benzhydrylamine → HCID 20292080, compound

HRID 1389207Notes

Reaction equation

HRID 1389207 reaction equation
Br[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][C:7]([O:9][CH2:10][CH3:11])=[O:8].[CH:12]([NH2:25])([C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1)[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>C1CCCCC1>[CH2:10]([O:9][C:7](=[O:8])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2][NH:25][CH:12]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1)[CH3:11]

Participants

4

Reactant 2

HCID 7036BenzhydrylamineHCID 117544Ethyl 6-bromohexanoate

Product 1

HCID 20292080HCID 20292080, compoundYield 69.2%

Reagents, catalysts & solvents 1

HCID 8078CyclohexaneSolvent

Procedure

22.3 g of ethyl 6-bromocaproate, 55 g of benzhydrylamine and 30 ml of cyclohexane are stirred at room temperature for 20 days. Preparation analogously to Example 19 yields 22.5 g (69% of theory) of ethyl-6-benzhydrylaminocaproate [B.P. 162° to 167° (0.02 mm Hg)].

Workup

  1. customPreparation analogously to Example 19

Sources & evidence

ORD record
ord-e93d4cf90b284110a4ccdcd128247057
Source dataset
uspto-grants-1981_01
Patent number
US04243678

Reaction notes

Loading…