HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethyl Sulfoxide → HCID 20292210, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethyl Sulfoxide | HCID 679 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | trans-Crotonyl chloride | HCID 643131 | — |
| Reactant | HCID 20292147 | HCID 20292147 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | HCID 20292210 | HCID 20292210 | 99.6% |
Reaction Steps
Analogously to Example 19, 7 g of ethyl 5-benzhydrylaminovalerate and 3.2 g of ethyldiisopropylamine are dissolved in 100 ml of benzene and reacted with 2.6 g of crotonyl chloride. As reaction product one obtains 8.5 g of ethyl N-crotonoyl-5-benzhydrylaminovalerate as a viscous non-distillable oil. The saponification of this ester yields 6 g (76%) of N-crotonoyl-5-benzhydrylaminovaleric acid (M.P. 88° to 89°).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04243678 |
| Source dataset | uspto-grants-1981_01 |
| ORD ID | ord-44f830f5e8524d478da28f8747d1af82 |
| Source note | uspto-grants-1981_01 |