Diisopropylethylamine → HCID 20298347, compound

Participants

Reaction Steps

13.3 g of 5-aminoindane, 23.0 g of ethyl 5-bromovalerate and 14.2 g of ethyl diisopropylamine are stirred together for 12 hours at 50°. After addition of diethyl ether thereto, the resulting precipitate is filtered off, the solvent is removed, and all volatile components are distilled off from the residue at 50° under a pressure of 10-2 mm Hg. The residue (which is left) is recrystallized from petrol ether to obtain 8.3 g (55.7% of theory) of ethyl 5-(indan-5-ylamino)valerate, MP 61° to 63°.

Provenance & Evidence