Sodium borohydride → HCID 20298680, compound

HRID 1389253Notes

Reaction equation

HRID 1389253 reaction equation
[CH3:1][N:2]([CH3:25])[CH2:3][CH2:4][CH2:5][O:6][C:7]1[CH:12]=[CH:11][C:10]([O:13][CH3:14])=[CH:9][C:8]=1[CH:15]=[N:16][CH2:17][CH2:18][C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1.[BH4-].[Na+]>CO>[CH3:25][N:2]([CH3:1])[CH2:3][CH2:4][CH2:5][O:6][C:7]1[CH:12]=[CH:11][C:10]([O:13][CH3:14])=[CH:9][C:8]=1[CH2:15][NH:16][CH2:17][CH2:18][C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1

Participants

4

Reactant 2

HCID 4311764Sodium borohydrideHCID 20298677HCID 20298677, compound

Product 1

HCID 20298680HCID 20298680, compoundYield 74.7%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

N-[[2-[3-(Dimethylamino)propoxy]-5-methoxylphenyl]-methylene]benzeneethanamine (39.5 g) is reduced with 13.0 g of sodium borohydride in 200 ml of methanol following the procedure described in Example 1C yielding 29.7 g of the title compound, boiling point 205°-210° C. at 0.4-0.5 mm of Hg.

Sources & evidence

ORD record
ord-c7b11abe4c2048ab8764f431cccdf61c
Source dataset
uspto-grants-1981_01
Patent number
US04243804

Reaction notes

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