HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium borohydride → N-[[3-Methoxy-2-[3-(4-morpholinyl)propoxy]phenyl]methyl]benzeneethanamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | N-[[3-Methoxy-2-[3-(4-morpholinyl)propoxy]phenyl]methylene]benzeneethanamine | HCID 20298672 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | N-[[3-Methoxy-2-[3-(4-morpholinyl)propoxy]phenyl]methyl]benzeneethanamine | HCID 20298679 | 80.5% |
Reaction Steps
N-[[3-Methoxy-2-[3-(4-morpholinyl)propoxy]phenyl]methylene]benzeneethanamine (49.7 g) is reduced with 14.8 g of sodium borohydride in 225 ml of methanol following the procedure described in Example 1C, yielding 40.2 g of the title compound, boiling point 0.2-0.3 mm of Hg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04243804 |
| Source dataset | uspto-grants-1981_01 |
| ORD ID | ord-e06592ba881c46bfbda1ba0370d0291d |
| Source note | uspto-grants-1981_01 |