Acetone → phenyl-Alanine

Participants

Reaction Steps

Following the same mode of operation as in the above example, starting with 0.14 g (approx. 10-3 mol) of α-hydroxyphenyl propionitrile in 2 ml of 0.1 M solution in KCN and 0.2 M in NH4OH 10 N, and after adding 0.06 g of acetone and 0.11 ml of NaOH 10 N after neutralisation, quantitative analysis by an analyst of α-amino acids gave a yield of 85% of phenyl alanine.

Provenance & Evidence