HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → (4-Fluorophenylthio)acetyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 2-[(4-Fluorophenyl)sulfanyl]acetic acid | HCID 736197 | — |
| Product | (4-Fluorophenylthio)acetyl chloride | HCID 13076191 | 88% |
Reaction Steps
A mixture of 5.3 g of (4-fluorophenylthio)acetic acid and 6.8 g of thionyl chloride is refluxed for 2 hours. Excess of thionyl chloride is evaporated in vacuo and the residue distilled. There are obtained 5.1 g (88%) of oily (4-fluorophenylthio)acetyl chloride, b.p. 76°-77° C./0.25 Torr.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04243805 |
| Source dataset | uspto-grants-1981_01 |
| ORD ID | ord-490eada3ec7f42a4a9a4961ce81a8b3d |
| Source note | uspto-grants-1981_01 |