4-((Trifluoromethyl)thio)aniline → HCID 54446014, compound

HRID 1389378Notes

Reaction equation

HRID 1389378 reaction equation
[F:1][C:2]([S:5][C:6]1[CH:11]=[CH:10][C:9]([NH2:12])=[CH:8][CH:7]=1)([F:4])[F:3].Br[CH:14]([CH:32]([CH3:34])[CH3:33])[C:15]([O:17]CC1C=CC=C(OC2C=CC=CC=2)C=1)=[O:16]>>[F:1][C:2]([F:4])([F:3])[S:5][C:6]1[CH:11]=[CH:10][C:9]([NH:12][C@H:14]([C:15]([OH:17])=[O:16])[CH:32]([CH3:34])[CH3:33])=[CH:8][CH:7]=1

Participants

3

Reactant 2

HCID 1230544-((Trifluoromethyl)thio)anilineHCID 13229492m-Phenoxybenzyl alpha-bromoisovalerate

Product 1

HCID 54446014HCID 54446014, compound

Procedure

Following the procedure of Example 43, p-aminophenyl trifluoromethyl sulfide is reacted with m-phenoxybenzyl α-bromoisovalerate to yield the m-phenoxybenzyl ester of N-(4-trifluoromethylthiophenyl)valine, MS m/e 475 (M+).

Sources & evidence

ORD record
ord-4127ae6b6a224f468cbc911dc5c2c6aa
Source dataset
uspto-grants-1981_01
Patent number
US04243819

Reaction notes

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