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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1389389Generated: November 1, 2026

4-Chloroaniline → N-(p-chlorophenyl)valine

https://huagongshe.com/reaction/1389389

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-ChloroanilineHCID 7812—
ReactantHCID 54165588HCID 54165588—
ReactantHCID 54382942HCID 54382942—
ProductN-(p-chlorophenyl)valineHCID 13796078—

Reaction Steps

Following the procedure of Example 6, 4-chloroaniline is reacted with each of p-benzylbenzyl α-bromoisovalerate and m-benzyl-α-cyanobenzyl α-bromoisovalerate to yield the p-benzylbenzyl ester of N-(4-chlorophenyl)valine, MS m/e 407 (M+), and the m-benzyl-α-cyanobenzyl ester of N-(4-chlorophenyl)valine, MS m/e 432 (M+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04243819
Source datasetuspto-grants-1981_01
ORD IDord-0fdb4911547e493190620bbfade0483c
Source noteuspto-grants-1981_01