反应详情

To 0.1 mole of α-amino-4-hydroxybenzeneacetic acid dissolved in 500 ml of water containing 0.05 mole of acetic acid is added 0.11 mole of methyl isocyanate. This mixture is stirred for 30 minutes at room temperature. The reaction mixture is saturated with sodium chloride and then extracted with ethyl acetate. The ethyl acetate is washed with water, dried over magnesium sulfate, filtered and evaporated to give the title compound.

1. extractionextracted with ethyl acetate
2. washThe ethyl acetate is washed with water
3. dry with materialdried over magnesium sulfate
4. filtrationfiltered
5. customevaporated