反应详情

A mixture of 0.2 g of 8-chloro-6-(2-fluorophenyl)-1-methyl-3-morpholino-4H-imidazo[1,5-a][1,4]-benzodiazepine 5-oxide, 0.2 ml of hexachlorodisilane and 10 ml of methylene chloride was allowed to sit for two days. It was then diluted with toluene and washed with 1 N sodium hydroxide solution. The organic phase was dried and evaporated. Crystallization of the residue from ether/hexane gave end product with mp 172°-174° C.

1. washwashed with 1 N sodium hydroxide solution
2. customThe organic phase was dried
3. customevaporated
4. customCrystallization of the residue from ether/hexane
5. customgave end product with mp 172°-174° C.