HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl formate → HCID 10352196, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl formate | HCID 8025 | — |
| Reactant | (3-Methoxyphenyl)acetonitrile | HCID 88310 | — |
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Product | HCID 10352196 | HCID 10352196 | — |
Reaction Steps
In a manner similar to Example 7, m-methoxyphenylacetonitrile is treated with sodium methoxide and ethyl formate to afford α-formyl-(3-methoxyphenyl)acetonitrile. Hydrogenation of this product yields 3-amino-2-(3-methoxyphenyl)-2-propenal which is condensed with dimethyl malonate to afford the product of the Example.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04244953 |
| Source dataset | uspto-grants-1981_01 |
| ORD ID | ord-b26a1e050fe142e781b290091fd96847 |
| Source note | uspto-grants-1981_01 |