HCID 20296349, compound → HCID 20296336, compound

HRID 1389447Notes

Reaction equation

HRID 1389447 reaction equation
[NH:1]([C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([O:15][CH3:16])[CH:10]=2)=[CH:5][N:4]=1)[NH2:2].[CH:17]([O-])([O-])OCC>>[CH3:16][O:15][C:11]1[CH:10]=[C:9]([C:6]2[CH:7]=[CH:8][C:3]3[N:4]([CH:17]=[N:2][N:1]=3)[CH:5]=2)[CH:14]=[CH:13][CH:12]=1

Participants

3

Reactant 2

HCID 20296349HCID 20296349, compoundHCID 53630039Ethylorthoformate

Product 1

HCID 20296336HCID 20296336, compound

Procedure

In a manner similar to Example 8, 2-hydrazino-5-(3-methoxyphenyl)pyridine is treated with ethyl orthoformate to give 6-(3-methoxyphenyl)-1,2,4-triazolo[4,3-a]pyridine. Hydrogenation of this product affords the product of the Example.

Sources & evidence

ORD record
ord-b0211fa38b84453fbc5b605266cba7e2
Source dataset
uspto-grants-1981_01
Patent number
US04244953

Reaction notes

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