3-Methyl-6-(4-nitrophenyl)-1,2,4-triazolo[4,3-a]pyridine → 6-(4-Aminophenyl)-3-methyl-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyridine

HRID 1389455Notes

Reaction equation

HRID 1389455 reaction equation
[CH3:1][C:2]1[N:6]2[CH:7]=[C:8]([C:11]3[CH:16]=[CH:15][C:14]([N+:17]([O-])=O)=[CH:13][CH:12]=3)[CH:9]=[CH:10][C:5]2=[N:4][N:3]=1.[H][H]>[Pd]>[NH2:17][C:14]1[CH:15]=[CH:16][C:11]([CH:8]2[CH2:7][N:6]3[C:2]([CH3:1])=[N:3][N:4]=[C:5]3[CH2:10][CH2:9]2)=[CH:12][CH:13]=1

Participants

4

Reactant 2

HCID 202963183-Methyl-6-(4-nitrophenyl)-1,2,4-triazolo[4,3-a]pyridineHCID 178418361HCID 178418361, compound

Product 1

HCID 202963166-(4-Aminophenyl)-3-methyl-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyridine

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

3-Methyl-6-(4-nitrophenyl)-1,2,4-triazolo[4,3-a]pyridine is treated with hydrogen in the presence of palladium on carbon to give the product of the Example.

Workup

  1. customto give the product of the Example

Sources & evidence

ORD record
ord-a0450314d16c43c9945549d999bd27be
Source dataset
uspto-grants-1981_01
Patent number
US04244953

Reaction notes

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