HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Phenyl-8-carbobenzyloxy-1-oxa-3,8-diazaspiro[4.5]decan-2-one → 3-Phenyl-1-oxa-3,8-diazaspiro(4.5)decan-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Phenyl-8-carbobenzyloxy-1-oxa-3,8-diazaspiro[4.5]decan-2-one | HCID 13016599 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3-Phenyl-1-oxa-3,8-diazaspiro(4.5)decan-2-one | HCID 20286475 | 113.7% |
Reaction Steps
A mixture of 3.4 g 3-phenyl-8-carbobenzyloxy-1-oxa-3,8-diazaspiro[4.5]decan-2-one, 50 ml ethanol and 0.4 g, 10% palladium on carbon is hydrogenated at room temperature and 60 psi for 6 hours. Filtration and removal of solvent affords 2.45 g 3-phenyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one, a pasty solid; m/e=232 (M+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04244961 |
| Source dataset | uspto-grants-1981_01 |
| ORD ID | ord-5ed62e07a7b440f6b9702781cd1d6450 |
| Source note | uspto-grants-1981_01 |